Which of the following is a FALSE statement regarding epithelial tissue structure?

Epithelial tissue is characterized by its high cellular density and minimal extracellular matrix. This type of tissue consists of tightly packed cells with very little space between them, which is essential for forming protective barriers and facilitating absorption and secretion. The primary role of epithelial tissue is to cover and line surfaces, which requires a configuration where cells are close together, rather than intermixed with a significant amount of matrix.

In contrast, connective tissues typically have a larger matrix compared to cellular content, which provides support and structure throughout the body. Thus, the assertion that epithelial tissue has a small cellular content with a large amount of matrix is incorrect, making this statement false.

The other statements accurately reflect certain characteristics of epithelial tissues: they do indeed have a direct nerve supply, allowing for sensation, and they receive their blood supply indirectly from underlying connective tissues through diffusion, as they are avascular. These properties highlight the unique nature of epithelial tissue in comparison to other tissue types.