Which of the following is TRUE about connective tissue?

Connective tissue is indeed histologically variable, which means that it can have a wide range of structures and functions depending on its type. This variance encompasses everything from the dense, closely packed fibers found in tendons to the loose, flexible matrix found in adipose tissue. The diversity in connective tissue types allows them to perform various roles in the body, including providing support, connecting different tissues, and storing energy.

The other statements are not accurate representations of connective tissue. It does not possess a free apical surface like epithelial tissue, which has cells oriented toward the body cavity or external environment. While many connective tissues are highly vascularized, they are not always avascular; cartilage, for example, is a type of connective tissue that can lack direct blood supply. Lastly, connective tissue is characterized by an abundance of extracellular matrix relative to the number of cells; hence, it is not composed solely of tightly packed cells but rather comprises cells scattered throughout a network of fibers and ground substance.