Which vitamin type is less likely to cause toxicity when prescribed in larger doses?

Water-soluble vitamins, such as vitamin C and the B vitamins, are generally less likely to cause toxicity even when taken in larger doses compared to fat-soluble vitamins. This is primarily because water-soluble vitamins are not stored in the body's tissues to a significant extent; instead, they are excreted through urine and other bodily fluids. When consumed in excess, the excess amounts are typically eliminated, reducing the risk of accumulation and subsequent toxicity.

In contrast, fat-soluble vitamins like A, D, E, and K can be stored in the body's fatty tissues and liver. This storage capability means that high doses can lead to a build-up over time, which increases the likelihood of toxicity. Fat-soluble vitamins are therefore associated with higher toxicity risks when taken in large amounts or over extended periods.

Amino acids and minerals have their own specific toxicity profiles; certain amino acids can cause adverse effects if taken in excessive amounts, and some minerals can be toxic when consumed in high quantities. However, the water-soluble vitamins stand out due to their relatively safe profile regarding overdose when compared to the other options.